ETHYL 3-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)BENZOATE - Names and Identifiers
Name | ethyl 3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzoate
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Synonyms | 3-Ethoxycarbonylphenylboronicacid pinacol 3-carboethoxyphenylboronic acid pinacol ester 3-ETHOXYCARBONYLPHENYLBORONIC ACID, PINACOL ESTER 3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)benzoate ETHYL 3-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)BENZOATE ethyl 3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzoate 3-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)ETHYL BENZOATE Benzoic acid, 3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-, ethyl ester 3-Carboethoxyphenylboronic acid pinacol ester, Ethyl 3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzoate
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CAS | 269410-00-6
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InChI | InChI=1/C15H21BO4/c1-6-18-13(17)11-8-7-9-12(10-11)16-19-14(2,3)15(4,5)20-16/h7-10H,6H2,1-5H3 |
ETHYL 3-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)BENZOATE - Physico-chemical Properties
Molecular Formula | C15H21BO4
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Molar Mass | 276.14 |
Density | 1.07±0.1 g/cm3(Predicted) |
Melting Point | 40-44°C(lit.) |
Boling Point | 378.6±25.0 °C(Predicted) |
Flash Point | >230°F |
Vapor Presure | 6.21E-06mmHg at 25°C |
Appearance | Powder |
Color | white |
Storage Condition | Inert atmosphere,Room Temperature |
Refractive Index | 1.497 |
MDL | MFCD03093896 |
ETHYL 3-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)BENZOATE - Risk and Safety
Hazard Symbols | Xi - Irritant
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Risk Codes | 36/37/38 - Irritating to eyes, respiratory system and skin.
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Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S36 - Wear suitable protective clothing.
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WGK Germany | 3 |
ETHYL 3-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)BENZOATE - Introduction
ethyl 3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzoate is an organic compound with the chemical formula C15H19BO4. The following is a description of its nature, use, preparation and safety information:
Nature:
-Appearance: Colorless liquid or solid
-Density: approx. 1.09g/cm³
-Melting point: about 35-40 ° C
-Boiling point: about 330-335 ° C
-Solubility: Soluble in organic solvents, such as ethanol, dimethylformamide
Use:
- ethyl 3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzoate is an important organic synthesis intermediate, widely used in organic synthesis reactions.
-It is often used in chemical reactions to build C- C bonds, C- N bonds and C- O bonds, such as Suzuki coupling reaction, Heck coupling reaction, etc.
Method:
ethyl 3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzoate is prepared as follows:
1. First prepare 4,4,5,5-tetramethyl -1,3, 2-dioxaborolone (also known as pynalol).
2. Reaction of 3-bromobenzoate with 3-bromobenzoate to obtain 3-bromobenzoate.
3. Finally, 3-bromophenylnaphthol Ester is reacted with trimethylphenylboronic acid to obtain ethyl 3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzoate.
Safety Information:
ethyl 3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzoate is a chemical and should be aware of the following safety precautions:
-It may cause irritation to the skin, eyes and mucous membranes, so use personal protective equipment such as lab gloves and goggles.
-Avoid inhaling its vapor or dust, and should be used in a well-ventilated place.
-Avoid direct contact or accidental ingestion, such as accidental contact, please immediately rinse with plenty of water, and seek medical help.
-When using and storing, please observe the relevant safety procedures.
Last Update:2024-04-10 22:29:15